Basic Information
VIS ID
TVIS44027221
Fusion event
HTLV-1-MAP2K5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q23
Reference genome
GRCh37/hg19
Start
67851073/67558735 (Hg38)
End
67851073/67558735 (Hg38)
Orient
-
Location type
Intronic
Target gene
MAP2K5
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-214-3p ; hsa-mir-330-3p
Nearest miRNA
hsa-mir-10393/Upstream/1061701; hsa-mir-11181/Downstream/1243115;
Nearest TSS
ENST00000557528/Upstream/9737; ENST00000439036/Downstream/4565;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/15563, chr15-CpG: 29/Downstream/262168
Upstream sequence
tctctgaacccgtgtgtttctccccaaacctctcattctgttctagccactctggcttcctttcggtctgtcaaacatgccaggcattcctctgacccag
Downstream sequence
ggcctttgtattagctgctgcctctgcctggaacagtctttccccagatatcagcaaggcccactccctcacctccttcagtctctttccactagagtgt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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