Basic Information
VIS ID
TVIS44027235
Fusion event
HTLV-1-PSTPIP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
77310806/77018465 (Hg38)
End
77310806/77018465 (Hg38)
Orient
+
Location type
Exonic
Target gene
PSTPIP1
miRNAs that regulate target gene
hsa-mir-629-3p ; hsa-mir-6867-3p ; hsa-mir-4713-5p
Nearest miRNA
hsa-mir-10393/Upstream/1256150; hsa-mir-11181/Downstream/2191323;
Nearest TSS
ENST00000557528/Upstream/7; ENST00000561315/Downstream/9260;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/86340, chr15-CpG: 24/Downstream/9344
Upstream sequence
TTTAAAAAACTCTTCTGTGTTCCCTCAAACCTGGGCCTCCCCCAGAGGTGGCAAGTCACTGATGATCTTTCAAATGCCCTTTTTTTTGCAGGGCCCAGGC
Downstream sequence
GGAGGAGCGGTACGGGAAGGAGCTGGTGCAGATCGCACGGAAGGCAGGTGGCCAGACGGAGATCAAGTAAGATCTCCCGGGCCCTGGGGCTCACTCCTCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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