Basic Information
VIS ID
TVIS44027247
Fusion event
HTLV-1-SH3GL3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q25.2
Reference genome
GRCh37/hg19
Start
84151901/83483149 (Hg38)
End
84151901/83483149 (Hg38)
Orient
+
Location type
Intronic
Target gene
SH3GL3
miRNAs that regulate target gene
hsa-mir-196a-5p
Nearest miRNA
hsa-mir-10393/Upstream/415734; hsa-mir-11181/Downstream/1897447;
Nearest TSS
ENST00000557528/Upstream/35618; ENST00000467735/Downstream/126121;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/34980, chr15-CpG: 159/Downstream/170421
Upstream sequence
TCATACTTACTTTGATTTCTCCAATTGGTTCTCTTATTTTAAATGACTGAGTTTCTTCATATGTTGGATTATTTTCTCCTATGCTCTTCAAAGAAAGTGG
Downstream sequence
CTCTAGTGTGTCTAGTTTCAGCAGGTGAGATATAGTCTGTTGTCAGCCCAGACAGGGTGAGAAGGGAGAGCTTCAGATTGATAGTTTAGCTTTCTGAAAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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