Basic Information
VIS ID
TVIS44027252
Fusion event
HTLV-1-RHCG integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q26.1
Reference genome
GRCh37/hg19
Start
90018418/89475187 (Hg38)
End
90018418/89475187 (Hg38)
Orient
+
Location type
Intronic
Target gene
RHCG
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-127-5p ; hsa-mir-7843-3p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-5197-5p ; hsa-mir-4786-3p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-466 ; hsa-mir-3941 ; hsa-mir-4643 ; hsa-mir-5011-5p ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-8485 ; hsa-mir-329-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-6740-3p ; hsa-mir-6131 ; hsa-mir-676-5p ; hsa-mir-3663-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-6748-3p ; hsa-mir-4733-3p ; hsa-mir-6513-3p ; hsa-mir-1911-3p
Nearest miRNA
hsa-mir-10393/Upstream/107081; hsa-mir-1302-10/Downstream/375450;
Nearest TSS
ENST00000557528/Upstream/88591; ENST00000567484/Downstream/4243;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/58428, chr15-CpG: 32/Downstream/11513
Upstream sequence
gcctgccttcattcattcctgcctgcctgccttcattcattcctgcctgccttccttcattccttccttccttcctgcctgcctgccttcctgcctgcct
Downstream sequence
gccttccttccttctttccttccttccttcctttttccttcttttctttccttccttttttttcttcctttttggtctcactctgtcatccaggctggag
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate