Basic Information
VIS ID
TVIS44027265
Fusion event
HTLV-1-IGF1R integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q26.3
Reference genome
End
99504356/98961127 (Hg38)
Orient
-
Location type
UTR3
Target gene
miRNAs that regulate target gene
hsa-mir-122-5p ; hsa-mir-133b ; hsa-mir-145-5p ; hsa-mir-7-5p ; hsa-mir-138-5p ; hsa-mir-194-5p ; hsa-mir-99a-5p ; hsa-mir-223-3p ; hsa-mir-100-5p ; hsa-mir-497-5p ; hsa-mir-152-3p ; hsa-mir-139-5p ; hsa-mir-376c-3p ; hsa-mir-376a-3p ; hsa-mir-181b-5p ; hsa-mir-383-5p ; hsa-mir-335-5p ; hsa-mir-215-5p ; hsa-mir-183-5p ; hsa-mir-182-5p ; hsa-mir-196a-5p ; hsa-mir-192-5p ; hsa-mir-30a-5p ; hsa-let-7d-5p ; hsa-mir-1226-3p ; hsa-mir-484 ; hsa-mir-320a ; hsa-mir-34a-5p ; hsa-mir-92a-3p ; hsa-let-7e-5p ; hsa-mir-125b-2-3p ; hsa-let-7c-5p ; hsa-mir-16-5p ; hsa-mir-630 ; hsa-let-7b-5p ; hsa-mir-143-3p ; hsa-mir-133a-3p ; hsa-mir-140-5p ; hsa-mir-150-3p ; hsa-mir-375 ; hsa-mir-511-3p ; hsa-mir-548n ; hsa-mir-548t-5p ; hsa-mir-3609 ; hsa-mir-548ah-5p ; hsa-mir-548at-5p ; hsa-mir-548az-5p ; hsa-let-7a-2-3p ; hsa-let-7g-3p ; hsa-mir-503-5p ; hsa-mir-4670-3p ; hsa-mir-583 ; hsa-mir-885-5p ; hsa-mir-4668-5p ; hsa-mir-6124 ; hsa-mir-7151-5p ; hsa-let-7a-5p ; hsa-let-7f-5p ; hsa-mir-33a-3p ; hsa-mir-98-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-577 ; hsa-mir-1294 ; hsa-mir-3927-3p ; hsa-mir-3935 ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-mir-5586-3p ; hsa-mir-6740-5p ; hsa-mir-6831-5p ; hsa-mir-1275 ; hsa-mir-4665-5p ; hsa-mir-3919 ; hsa-mir-8485 ; hsa-mir-625-5p ; hsa-mir-3148 ; hsa-mir-4641 ; hsa-mir-4710 ; hsa-mir-4792 ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-302d-3p ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-520e ; hsa-mir-520a-3p ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-520d-3p ; hsa-mir-1253 ; hsa-mir-302e ; hsa-mir-4299 ; hsa-mir-3646 ; hsa-mir-3662 ; hsa-mir-6770-5p ; hsa-mir-7855-5p ; hsa-mir-99b-5p ; hsa-mir-378a-3p ; hsa-mir-224-3p ; hsa-mir-522-3p ; hsa-mir-1468-3p ; hsa-mir-885-3p ; hsa-mir-3613-3p ; hsa-mir-190a-3p ; hsa-mir-1277-5p ; hsa-mir-5011-5p ; hsa-mir-548d-3p ; hsa-mir-548h-3p ; hsa-mir-548z ; hsa-mir-548ac ; hsa-mir-548as-3p ; hsa-mir-548bb-3p ; hsa-mir-5681a ; hsa-mir-34a-3p ; hsa-mir-539-5p ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-3617-3p ; hsa-mir-6511a-5p ; hsa-mir-8060 ; hsa-mir-96-5p ; hsa-mir-1271-5p ; hsa-mir-3125 ; hsa-mir-3916 ; hsa-mir-6859-5p ; hsa-mir-592 ; hsa-mir-597-5p ; hsa-mir-520a-5p ; hsa-mir-525-5p ; hsa-mir-2467-3p ; hsa-mir-185-5p ; hsa-mir-206 ; hsa-mir-21-5p ; hsa-mir-26b-5p ; hsa-mir-486-5p ; hsa-mir-218-5p ; hsa-mir-4535 ; hsa-mir-4800-5p ; hsa-mir-8071 ; hsa-mir-6745 ; hsa-mir-363-5p ; hsa-mir-8085 ; hsa-mir-3175 ; hsa-mir-6731-5p ; hsa-mir-659-5p ; hsa-mir-492 ; hsa-mir-6861-3p ; hsa-mir-6804-5p ; hsa-mir-5572 ; hsa-mir-4260 ; hsa-mir-450a-2-3p ; hsa-mir-6803-5p ; hsa-mir-6751-5p ; hsa-mir-7109-5p ; hsa-mir-4789-5p ; hsa-mir-466 ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-202-3p ; hsa-mir-3163 ; hsa-mir-4643 ; hsa-mir-4789-3p ; hsa-mir-340-5p ; hsa-mir-4539 ; hsa-mir-3200-5p ; hsa-mir-7161-5p ; hsa-mir-548u ; hsa-mir-3191-5p ; hsa-mir-6873-3p ; hsa-mir-7978 ; hsa-mir-494-3p ; hsa-mir-4456 ; hsa-mir-548q ; hsa-mir-6824-3p ; hsa-mir-6764-3p ; hsa-mir-518c-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-4423-3p ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-551b-5p ; hsa-mir-548c-3p ; hsa-mir-675-3p ; hsa-mir-223-5p ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-4655-5p ; hsa-mir-224-5p ; hsa-mir-502-5p ; hsa-mir-3941 ; hsa-mir-3124-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-4433b-5p ; hsa-mir-203a-3p ; hsa-mir-6794-3p ; hsa-mir-377-3p ; hsa-mir-4433a-5p ; hsa-mir-342-3p ; hsa-mir-6884-3p ; hsa-mir-4639-3p ; hsa-mir-4511 ; hsa-mir-629-3p ; hsa-mir-3180-5p ; hsa-mir-488-5p ; hsa-mir-7161-3p ; hsa-mir-6738-3p ; hsa-mir-544a ; hsa-mir-5001-3p ; hsa-mir-4727-5p ; hsa-mir-570-3p ; hsa-mir-125b-1-3p ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-6727-5p ; hsa-mir-6084 ; hsa-mir-6762-3p ; hsa-mir-4755-3p ; hsa-mir-6774-5p ; hsa-mir-635 ; hsa-mir-4508 ; hsa-mir-6775-5p ; hsa-mir-5090 ; hsa-mir-10b-3p ; hsa-mir-6867-5p ; hsa-mir-5003-5p ; hsa-mir-15b-3p ; hsa-mir-7-1-3p ; hsa-mir-125b-5p ; hsa-mir-141-3p ; hsa-mir-214-5p ; hsa-mir-448 ; hsa-mir-217
Nearest miRNA
hsa-mir-10393/Upstream/176625; hsa-mir-1302-10/Downstream/2999332;
Nearest cancer related gene
IGF1R(OG, No orient, 0)
Upstream sequence
GGCAGCTTTGCCTAAGCGTGGATGGCTCCTCGGCAATTCCAGCCTAAGTGAAGGCGCTCAGGAGCCTCCTGCTGGAACGCGACCCATCTCTCCCAGGACC
Downstream sequence
CCGGGGATCTTAAGGTCATTGAGAAATACTGTTGGATCAGGGTTTTGTTCTTCCACACTGTAGGTGACCCCTTGGAATAACGGCCTCTCCTCTCGTGCAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate