Basic Information
VIS ID
TVIS44027275
Fusion event
HTLV-1-NOMO1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.11
Reference genome
GRCh37/hg19
Start
14940576/14846719 (Hg38)
End
14940576/14846719 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA16A
Target gene
NOMO1
miRNAs that regulate target gene
hsa-mir-10a-5p ; hsa-mir-675-5p
Nearest miRNA
hsa-mir-1225/Upstream/537348; hsa-mir-11401/Downstream/54789;
Nearest TSS
ENST00000527434/Upstream/12901; ENST00000566720/Downstream/1802;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/12535, chr16-CpG: 166/Downstream/64230
Upstream sequence
TGTCTCTGAGAAACACTGGGACCGAAGCAAAGATCCAGTCCACAGTTACACAGCCTGGCGGAAAGTGAGTAGCGTCCTGTCTCTTAGTGTTGCCTTAGAG
Downstream sequence
CCGGGCTCTGACAGGGGTCATGGAGCTGGGTTTGggagtttggattcagggagttctgggttcagatcctgattcagcctctttgggtgagttcatgccc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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