Basic Information
VIS ID
TVIS44027288
Fusion event
HTLV-1-KCTD5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
2749866/2699865 (Hg38)
End
2749866/2699865 (Hg38)
Orient
-
Location type
Exonic
Target gene
KCTD5
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-92a-3p ; hsa-mir-26a-5p ; hsa-mir-125a-3p ; hsa-mir-134-5p ; hsa-mir-155-5p ; hsa-mir-583 ; hsa-mir-1255a ; hsa-mir-1255b-5p ; hsa-mir-3118 ; hsa-mir-3128 ; hsa-mir-3605-5p ; hsa-mir-6894-5p ; hsa-mir-4470 ; hsa-mir-3135a ; hsa-mir-873-5p ; hsa-mir-6089 ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-34a-3p ; hsa-mir-5008-5p ; hsa-mir-30a-5p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30e-5p ; hsa-mir-3194-3p ; hsa-mir-3607-3p ; hsa-mir-3686 ; hsa-mir-5096 ; hsa-mir-5691 ; hsa-mir-6767-5p ; hsa-mir-6805-3p ; hsa-mir-7974
Nearest miRNA
hsa-mir-1225/Upstream/167860; hsa-mir-11401/Downstream/785516;
Nearest TSS
ENST00000527434/Upstream/14251; ENST00000574340/Downstream/15700;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/2755, chr16-CpG: 30/Downstream/7669
Upstream sequence
AGGCAGCAGTGGGACATGGGTGGCCCGCCCTTACCTGTGCCCATTGTCCTTGCAGGTGCCTGTGAAGCATGTGTACCGTGTGCTGCAGTGCCAGGAGGAG
Downstream sequence
GAGCTCACGCAGATGGTGTCCACCATGTCCGACGGCTGGAAGTTCGAGCAGGTGAGGGGCCCTGGCCAGCCTGGTGGCAGCCATGCTGCAGCTGAACTTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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