Basic Information
VIS ID
TVIS44027335
Fusion event
HTLV-1-OGFOD1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q13
Reference genome
GRCh37/hg19
Start
56485404/56451492 (Hg38)
End
56485404/56451492 (Hg38)
Orient
+
Location type
Intronic
Target gene
OGFOD1
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-155-5p ; hsa-mir-34a-5p ; hsa-mir-30a-5p ; hsa-mir-615-3p ; hsa-mir-222-3p ; hsa-mir-4668-5p ; hsa-mir-3613-3p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-4284 ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-4772-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-1304-3p ; hsa-mir-6741-3p ; hsa-mir-1281 ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-660-3p ; hsa-mir-4485-5p ; hsa-mir-6890-3p ; hsa-mir-5571-5p ; hsa-mir-4279 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-939-3p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p
Nearest miRNA
hsa-mir-1225/Upstream/205869; hsa-mir-11401/Downstream/407026;
Nearest TSS
ENST00000527434/Upstream/2; ENST00000569645/Downstream/29;
Nearest CpG islands
chr16-CpG: 71/Target, None/Upstream, None/Downstream
Nearby gene
OGFOD1(+20) ;
Upstream sequence
CCTGCCAGACCGAGCTCCAGTGGGCCAATTGCTGGTGGGATGGCTGCAATAGCTGGAGCTCCCATTGGTAAACCGGGTATAGGTTCCGCCTTCTCTTACT
Downstream sequence
TTGGTGCTTCCCATTGGGTAGGGCCGGGAAACACGATAAAGGGGACATGCCGGGAGTTGCAGTACCCTCAGGAAGGTAGCGTCTTGATCTGCGTGGCGTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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