Basic Information
VIS ID
TVIS44027339
Fusion event
HTLV-1-MMP15 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q21
Reference genome
GRCh37/hg19
Start
58076776/58042872 (Hg38)
End
58076776/58042872 (Hg38)
Orient
+
Location type
Intronic
Target gene
MMP15
miRNAs that regulate target gene
hsa-mir-29b-3p ; hsa-mir-29c-3p ; hsa-mir-8057 ; hsa-mir-3915 ; hsa-mir-760 ; hsa-mir-6822-3p ; hsa-mir-3928-3p ; hsa-mir-3202 ; hsa-mir-7162-3p ; hsa-mir-4649-3p ; hsa-mir-4653-5p ; hsa-mir-3921 ; hsa-mir-3158-3p ; hsa-mir-6876-5p ; hsa-mir-4476
Nearest miRNA
hsa-mir-1225/Upstream/270520; hsa-mir-11401/Downstream/9159449;
Nearest TSS
ENST00000527434/Upstream/2707; ENST00000564672/Downstream/72578;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/2747, chr16-CpG: 31/Downstream/2174
Upstream sequence
CCACTGTCCTGAGCTTCAGTGAGGCAGGAGCTCCCTGAGGACAGGGCTGGCACCAAACTAAAAGCAGGGAGCCCTGGGCCACACACTGTGAGGGCTGCAG
Downstream sequence
GTGTGCTCCAGGGACACAGCCCCCAGACCCAGAGGCCAGGCAGTCCCCTCCCCATACAAGAACTATATGTGCGGGGGTGGATGTGCACATGGAAGCGAGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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