Basic Information
VIS ID
TVIS44027371
Fusion event
HTLV-1-TMEM231 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
75585239/75551341 (Hg38)
End
75585239/75551341 (Hg38)
Orient
-
Location type
Intronic
Target gene
TMEM231
miRNAs that regulate target gene
hsa-mir-561-5p ; hsa-mir-765 ; hsa-mir-4480 ; hsa-mir-6830-5p ; hsa-mir-371b-3p ; hsa-mir-6895-5p ; hsa-mir-4779 ; hsa-mir-6891-5p ; hsa-mir-3173-3p ; hsa-mir-4279 ; hsa-mir-24-2-5p ; hsa-mir-24-1-5p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-3121-3p
Nearest miRNA
hsa-mir-1225/Upstream/5520919; hsa-mir-11401/Downstream/1317595;
Nearest TSS
ENST00000527434/Upstream/5913; ENST00000621911/Downstream/3930;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/21127, chr16-CpG: 76/Downstream/4448
Upstream sequence
ggctagagtgcagtggcacgatcacagctcattgcagccttgacctctcaggctcaagtgatcctcccacctcagcctcctgagtagctgggactatagg
Downstream sequence
cattcaccactacccctggctaatttttaaattttttatagtagggcctcactatgttgcctaggcggtctggaactcctgagctcaaggggctagcctc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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