Basic Information
VIS ID
TVIS44027389
Fusion event
HTLV-1-EMC8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
85817371/85783765 (Hg38)
End
85817371/85783765 (Hg38)
Orient
-
Location type
Intronic
Target gene
EMC8
miRNAs that regulate target gene
hsa-mir-484 ; hsa-mir-5000-5p ; hsa-mir-3119 ; hsa-mir-4662a-3p ; hsa-mir-632 ; hsa-mir-4288 ; hsa-mir-500a-3p ; hsa-mir-346 ; hsa-mir-6804-3p ; hsa-mir-4793-3p ; hsa-mir-3130-3p ; hsa-mir-6761-5p ; hsa-mir-877-3p ; hsa-mir-211-3p ; hsa-mir-654-3p ; hsa-mir-7845-5p ; hsa-mir-483-5p ; hsa-mir-140-3p
Nearest miRNA
hsa-mir-12128/Upstream/42065; hsa-mir-11401/Downstream/134582;
Nearest TSS
ENST00000527434/Upstream/2005; ENST00000602706/Downstream/617;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/32240, chr16-CpG: 138/Downstream/15049
Upstream sequence
TGTGTCTTCAATGTCAGGAAATCTGCCTACATGTCATCTGCCTCACATGCCCGTCTTGTTTCACTCACACTGTCCCGTCTGGCCCTCCACACCAAGGCCT
Downstream sequence
CCTTACTGAATTGCTTCCCCTCTTTCAGTGCCCAGAAGACATGCCACCCTCACCACAAAGCCCTGCTAAACCCTGGATGAGACCCCCTGCCCTGCTGGAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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