Basic Information
VIS ID
TVIS44027393
Fusion event
HTLV-1-ZFPM1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
88526977/88460569 (Hg38)
End
88526977/88460569 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZFPM1
miRNAs that regulate target gene
hsa-mir-183-5p ; hsa-mir-200c-3p ; hsa-mir-142-3p ; hsa-mir-5682 ; hsa-mir-585-5p ; hsa-mir-4764-3p ; hsa-mir-601 ; hsa-mir-423-3p ; hsa-mir-500b-3p ; hsa-mir-6871-3p ; hsa-mir-29c-3p ; hsa-mir-29b-3p ; hsa-mir-29a-3p ; hsa-mir-4482-5p ; hsa-mir-3130-5p
Nearest miRNA
hsa-mir-11401/Upstream/606605; hsa-mir-4722/Downstream/8349;
Nearest TSS
ENST00000527434/Upstream/6942; ENST00000569435/Downstream/70484;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/4463, chr16-CpG: 40/Downstream/7420
Upstream sequence
GAAAAGGTCCTAAGGGGCCAGGACTCAAGTCCTGCCCTGGTGCGAGGAAGAAACAGGGGAGATGGTCTGGTCCTGCCCTCTGCCCAACACCAGCCTTCAT
Downstream sequence
GTTTAGCACGTGGCACTGACTTAAGGACCCCAGAGTGAGGATGGAGGGTGTGGCTCTCAGCCAGGTGGCCTCAGCCAATGCCCACCTTAGAGACTCCGCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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