Basic Information
VIS ID
TVIS44027398
Fusion event
HTLV-1-ABR integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
908638/1005398 (Hg38)
End
908638/1005398 (Hg38)
Orient
+
Location type
UTR3
Target gene
ABR
miRNAs that regulate target gene
hsa-mir-877-3p ; hsa-mir-93-3p ; hsa-mir-92b-3p ; hsa-mir-18a-5p
Nearest miRNA
hsa-mir-10226/Downstream/17078;
Nearest TSS
ENST00000595228/Upstream/8281; ENST00000438344/Downstream/4815;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/7875, chr17-CpG: 50/Downstream/1343
Upstream sequence
GAACAGGTAAACCCCAGAAGTGGAGATTCCCAAACGGAAAATTCCAGAAATGGGCGCTCCAGCTCTGTGCTAAGCTGGGGACGAGTGTGAGTGTGTCTGC
Downstream sequence
TTGTCCAACATTTGCACAGGCAGCAAGGCAAAGCAGGTGTGCTCCCAAAGGCGGAGTCTGAGGAGGGGCCGGCAGCGGCAAACGGCAGCATCAAACAGAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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