Basic Information
VIS ID
TVIS44027411
Fusion event
HTLV-1-NCOR1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p12
Reference genome
GRCh37/hg19
Start
15990889/16087575 (Hg38)
End
15990889/16087575 (Hg38)
Orient
-
Location type
Intronic
Target gene
NCOR1
miRNAs that regulate target gene
hsa-mir-1301-3p ; hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-320a ; hsa-let-7b-5p ; hsa-mir-34a-3p
Nearest miRNA
hsa-mir-1253/Upstream/835879; hsa-mir-10226/Downstream/194439;
Nearest TSS
ENST00000595228/Upstream/7062; ENST00000463810/Downstream/4343;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/87201, chr17-CpG: 118/Downstream/127386
Upstream sequence
AATTCACCCACAGAGAAGTTAAGAAATCCTGTAAATCTAAATCTCCTGTGTATCCTCAAAAATTCATTTACGAGTTTTCCCTTTAAAGGAAAAAGAACTT
Downstream sequence
CTCTTTCCTCTTAAGGAGAATCAAGTGTTTTCACATGCAATAAAATCACAACAGGCAAACATCAGATTATCAAGCAATTCTGTTAATTCAAATCTGGCCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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