Basic Information
VIS ID
TVIS44027425
Fusion event
HTLV-1-RAP1GAP2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
2712445/2809151 (Hg38)
End
2712445/2809151 (Hg38)
Orient
-
Location type
Intronic
Target gene
RAP1GAP2
miRNAs that regulate target gene
hsa-mir-652-3p ; hsa-mir-149-5p ; hsa-mir-222-3p ; hsa-mir-181b-5p ; hsa-mir-6085 ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-5010-5p ; hsa-mir-615-5p ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-6825-5p ; hsa-mir-7106-5p ; hsa-mir-5787 ; hsa-mir-4505 ; hsa-mir-765 ; hsa-mir-6738-5p ; hsa-mir-4731-5p ; hsa-mir-5194 ; hsa-mir-1914-3p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-4537 ; hsa-mir-637 ; hsa-mir-4720-3p ; hsa-mir-4804-3p ; hsa-mir-6793-3p
Nearest miRNA
hsa-mir-1253/Upstream/60969; hsa-mir-10226/Downstream/2160551;
Nearest TSS
ENST00000595228/Upstream/12669; ENST00000574515/Downstream/156744;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/31933, chr17-CpG: 200/Downstream/43656
Upstream sequence
CTCCTGGAGGTACCATTTGCCAGGCGGCAAGGTCTGCAGACTCCAAGACCCATGTGCTCCTGGCCCTCCTCCTGGCCAGTCCCTGCCATGCCCAGGAAGC
Downstream sequence
CCTGGTGAGTCCCTGTTCTGGTTTCTCATTGGACAAACAGCTCCCCGGACTTGGCCAGGTCTTGTGGGTATCTGCTGATGGGCAGGCAGGGAGCCGGCTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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