Basic Information
VIS ID
TVIS44027428
Fusion event
HTLV-1-BLMH integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
28585828/30258810 (Hg38)
End
28585828/30258810 (Hg38)
Orient
+
Location type
Intronic
Target gene
BLMH
miRNAs that regulate target gene
hsa-mir-1226-3p ; hsa-mir-484 ; hsa-mir-30c-5p ; hsa-mir-92a-3p ; hsa-mir-374a-3p ; hsa-mir-361-5p ; hsa-mir-4791 ; hsa-mir-3201 ; hsa-mir-144-5p ; hsa-mir-2115-3p ; hsa-mir-101-5p ; hsa-mir-186-5p ; hsa-mir-3679-3p ; hsa-mir-141-5p
Nearest miRNA
hsa-mir-1180/Upstream/141638; hsa-mir-10226/Downstream/835540;
Nearest TSS
ENST00000595228/Upstream/8527; ENST00000583275/Downstream/12683;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/22642, chr17-CpG: 92/Downstream/32542
Upstream sequence
CTCTGAGGGTGAACCCGGAGAGGAAAGCACAAATTTAGATGCCATCCAAGGGTCTTGTTTTCCCACTGAAACTCAATGACTTTTCTCTCACCCCAAACTA
Downstream sequence
TCGCTACTCCTATTTGTTTCAGACAAAGTCTGCTTGTCGGTCACTCCTCAAAAGCTCTGTGAATGGCAAGCCACATTATTTCTTGGCTTCACTCCTCTGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate