Basic Information
VIS ID
TVIS44027440
Fusion event
HTLV-1-TRPV1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
3488689/3585395 (Hg38)
End
3488689/3585395 (Hg38)
Orient
+
Location type
Intronic
Target gene
TRPV1
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-let-7e-5p ; hsa-mir-1228-3p ; hsa-mir-1247-3p ; hsa-mir-1273g-3p ; hsa-mir-1285-3p ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-196a-3p ; hsa-mir-298 ; hsa-mir-3187-5p ; hsa-mir-3612 ; hsa-mir-455-3p ; hsa-mir-4793-3p ; hsa-mir-495-5p ; hsa-mir-508-5p ; hsa-mir-5189-5p ; hsa-mir-612 ; hsa-mir-6499-3p ; hsa-mir-650 ; hsa-mir-6511a-5p ; hsa-mir-6512-3p ; hsa-mir-6516-5p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6807-5p ; hsa-mir-6849-3p ; hsa-mir-6860 ; hsa-mir-766-3p ; hsa-mir-7703 ; hsa-mir-939-3p
Nearest miRNA
hsa-mir-1253/Upstream/837213; hsa-mir-10226/Downstream/1384307;
Nearest TSS
ENST00000595228/Upstream/7507; ENST00000495445/Downstream/6955;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/13792, chr17-CpG: 17/Downstream/38554
Upstream sequence
caggctccaccacacccagttaatttggtgtttttagtagagacggggtttcaccatgttggtcaggctggtctcaaactccagacctcaggtgatctgc
Downstream sequence
ccacctcagcctcccaaagtgctgggattacaggcatgagccaccatgcccggccCCTGCATGCTTTCTAACCGAGTACACCCCGTCTACAATCAGGGAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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