Basic Information
VIS ID
TVIS44027454
Fusion event
HTLV-1-MYBBP1A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
4453600/4550305 (Hg38)
End
4453600/4550305 (Hg38)
Orient
+
Location type
Exonic
Target gene
MYBBP1A
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-26b-5p ; hsa-mir-30b-3p ; hsa-mir-193b-3p ; hsa-mir-331-3p ; hsa-mir-183-5p ; hsa-mir-92a-3p ; hsa-mir-3186-5p
Nearest miRNA
hsa-mir-1253/Upstream/1802123; hsa-mir-10226/Downstream/419397;
Nearest TSS
ENST00000595228/Upstream/128; ENST00000574133/Downstream/4607;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/13895, chr17-CpG: 73/Downstream/4583
Nearest cancer related gene
MYBBP1A(TSG, No orient, 0)
Upstream sequence
AAGTAGGCGTGACAGGGAGGCCTTGGTTGGTGACAGATGAGAAGGCCACTAGCACGGCCAGCTGCCGCTCAGGGTCATCCTGGCACCCCTCTAGGAAGGT
Downstream sequence
GCCCACGTAATCGTCCATCTCTGGGGCAAACTTGAACTGCTTTGGGAGCTGCAAGAGTTAGGCATGGCGCTGAGCCCACCAGCCCAGGGGGGCAGGCGGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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