Basic Information
VIS ID
TVIS44027461
Fusion event
HTLV-1-ITGA3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.33
Reference genome
End
48141659/50064295 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-1-3p ; hsa-mir-26b-5p ; hsa-mir-1273e ; hsa-mir-4266 ; hsa-mir-6807-5p ; hsa-mir-6894-5p ; hsa-mir-1233-3p ; hsa-mir-1225-3p ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4433a-3p ; hsa-mir-4779 ; hsa-mir-4695-5p ; hsa-mir-4668-5p ; hsa-mir-4652-3p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-7160-5p ; hsa-mir-202-3p ; hsa-mir-98-5p ; hsa-mir-4500 ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-7162-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-98-3p ; hsa-let-7f-1-3p ; hsa-let-7b-3p ; hsa-let-7a-3p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-4723-5p ; hsa-mir-5698 ; hsa-mir-6825-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-4457 ; hsa-mir-605-3p ; hsa-mir-4666a-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-6794-5p ; hsa-mir-4716-3p ; hsa-mir-5582-5p ; hsa-mir-6891-5p ; hsa-mir-3173-3p ; hsa-mir-199a-5p ; hsa-mir-199b-5p ; hsa-mir-199a-3p ; hsa-mir-199b-3p ; hsa-mir-101-3p ; hsa-mir-1255a ; hsa-mir-1255b-5p ; hsa-mir-1287-5p ; hsa-mir-136-3p ; hsa-mir-144-5p ; hsa-mir-192-5p ; hsa-mir-215-5p ; hsa-mir-3652 ; hsa-mir-3661 ; hsa-mir-3682-3p ; hsa-mir-4430 ; hsa-mir-4505 ; hsa-mir-5787 ; hsa-mir-631 ; hsa-mir-647 ; hsa-mir-6744-5p ; hsa-mir-6842-3p
Nearest miRNA
hsa-mir-10226/Upstream/553395; hsa-mir-1250/Downstream/704355;
Nearest cancer related gene
ITGA3(OG, No orient, 0)
Upstream sequence
CAGTGAAAAGTGAGGGGAAGGGGCTGGGGAGGGGTGCTGGGTCAGAGGTCTGGCAGGGGGGTACCGCAGAGAGAATGGCCTGGAGGAGATAGAAGGCTTG
Downstream sequence
TTCACACGGCTTCTAGTCGCTTCTTGTCCAGCTGGGAAGAGGGTGCCCTAGAGGAGAGTGGGGCTGGATGGGATTGGTAGAGCTCAGAATAATGACGAGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate