Basic Information
VIS ID
TVIS44027474
Fusion event
HTLV-1-BCAS3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
59314318/61236957 (Hg38)
End
59314318/61236957 (Hg38)
Orient
+
Location type
Intronic
Target gene
BCAS3
miRNAs that regulate target gene
hsa-mir-1278 ; hsa-mir-1285-3p ; hsa-mir-2861 ; hsa-mir-3187-5p ; hsa-mir-326 ; hsa-mir-330-5p ; hsa-mir-3664-5p ; hsa-mir-3667-3p ; hsa-mir-378g ; hsa-mir-4486 ; hsa-mir-4714-5p ; hsa-mir-514a-5p ; hsa-mir-5189-5p ; hsa-mir-612 ; hsa-mir-6734-3p ; hsa-mir-6860 ; hsa-mir-6883-3p
Nearest miRNA
hsa-mir-10226/Upstream/1193852; hsa-mir-1250/Downstream/1707258;
Nearest TSS
ENST00000595228/Upstream/77595; ENST00000587872/Downstream/8259;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/558838, chr17-CpG: 720/Downstream/158742
Upstream sequence
ttatgcagcaggaacaacacaaaggaaaaattggaggcaggaaagTTGGATCCTGGATGTGAAGGGAGGTAATAAAAGAGAAGACTGAAAAAGTAGAATA
Downstream sequence
GCCTCTGCATAGCGGACTTAGGATGCCAGGCCTGAGAGTGGACTTCCTTTGGTAAAGCAAGAGGAAGCCATTAAAAAGTTATCTTTTTTACATAGCTGTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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