Basic Information
VIS ID
TVIS44027479
Fusion event
HTLV-1-FTSJ3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
61899247/63821887 (Hg38)
End
61899247/63821887 (Hg38)
Orient
-
Location type
Intronic
Target gene
FTSJ3
miRNAs that regulate target gene
hsa-mir-330-5p ; hsa-mir-6769b-5p ; hsa-mir-6803-5p ; hsa-mir-6751-5p ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-491-5p ; hsa-mir-92a-2-5p ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-608 ; hsa-mir-4651 ; hsa-mir-7110-5p ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-6835-5p ; hsa-mir-6825-5p ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-3175 ; hsa-mir-27a-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-4721 ; hsa-mir-4720-3p ; hsa-mir-873-5p ; hsa-mir-506-5p ; hsa-mir-892c-5p ; hsa-mir-3158-3p ; hsa-mir-1265 ; hsa-mir-2392
Nearest miRNA
hsa-mir-10226/Upstream/877575; hsa-mir-1250/Downstream/678887;
Nearest TSS
ENST00000595228/Upstream/4814; ENST00000582420/Downstream/136;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/47185, chr17-CpG: 56/Downstream/5479
Upstream sequence
GTGGATTCTCCTCCTCCTCCTCCTCTTTATCATCTTGCACTTCAGTAAGTCGCATACTGTAGACCCAAAGGAAAGTAGGGGGCTCAGAGACCCAGATTGC
Downstream sequence
CTGGAGCCCTTGCTGCCCTACTCAGGCTCTGGTAGTACCCACCCTAACACTTCCTCAGAGTGGCAGCATTCCCTTTGGTGCACACGTGCCCCTTACCGCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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