Basic Information
VIS ID
TVIS44027499
Fusion event
HTLV-1-BCL6B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
6927672/7024353 (Hg38)
End
6927672/7024353 (Hg38)
Orient
-
Location type
Intronic
Target gene
BCL6B
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-1-3p
Nearest miRNA
hsa-mir-1253/Upstream/6331; hsa-mir-10226/Downstream/198944;
Nearest TSS
ENST00000595228/Upstream/876; ENST00000571729/Downstream/2148;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/145, chr17-CpG: 78/Downstream/11465
Nearest cancer related gene
BCL6B(TSG, No orient, 0)
Upstream sequence
TTTGCAGATGGAGCACGTGGTCCAGGCATGCCACCGCTTCATCCAGGCCAGGTGAGGGACCCTGGCTCGGCGTTCTCTGTGGGTGAGGTGTTAAGGGCAA
Downstream sequence
AGGCAGAGTTTAGGAAATGGCACTAACGTTCATCACACTTTCCCCAGCTATGAACCTCTGGGCATCTCCCTGCGCCCCCTGGAAGCAGAACCCCCAACAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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