Basic Information
VIS ID
TVIS44027551
Fusion event
HTLV-1-CDH2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
25740343/28160379 (Hg38)
End
25740343/28160379 (Hg38)
Orient
-
Location type
Intronic
Target gene
CDH2
miRNAs that regulate target gene
hsa-mir-204-5p ; hsa-mir-194-5p ; hsa-mir-145-5p ; hsa-mir-155-5p ; hsa-mir-138-5p ; hsa-mir-124-3p ; hsa-mir-1-3p ; hsa-mir-30a-5p ; hsa-mir-27b-5p ; hsa-mir-615-3p ; hsa-mir-218-5p ; hsa-mir-199a-5p ; hsa-mir-412-3p ; hsa-mir-411-5p ; hsa-mir-216b-3p ; hsa-mir-1244 ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-338-3p ; hsa-mir-506-3p ; hsa-mir-153-5p ; hsa-mir-208a-5p ; hsa-mir-208b-5p ; hsa-mir-587
Nearest miRNA
hsa-mir-1-2/Upstream/1568844; hsa-mir-122/Downstream/2138531;
Nearest TSS
ENST00000575820/Upstream/1082; ENST00000582726/Downstream/17067;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/974836, chr18-CpG: 257/Downstream/15071
Upstream sequence
CAATCTGGGTGAAAGCTGCCGCAATTTGGCCTTGGCAATGGTCTAAGGTAGCTCAGGACTCTGGAAGTGCTGAGGGGCCTCAGCTTGAACGTGCTGAGGG
Downstream sequence
GCATAAAAAGAGGATTATTTCAACATCTACTGCCTAAAGACTAGTCAATGAGCAATGTTTGTTATTTTTTAATAACACTGAGTTCAAGAACACTAGCAAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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