Basic Information
VIS ID
TVIS44027567
Fusion event
HTLV-1-COLEC12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
p11.32
Reference genome
GRCh37/hg19
Start
413264/413264 (Hg38)
End
413264/413264 (Hg38)
Orient
-
Location type
Intronic
Target gene
COLEC12
miRNAs that regulate target gene
hsa-mir-9-5p ; hsa-mir-7-5p ; hsa-mir-26b-5p ; hsa-mir-1303 ; hsa-mir-877-5p ; hsa-mir-6866-5p ; hsa-mir-4650-3p ; hsa-mir-4999-3p ; hsa-mir-3927-3p ; hsa-mir-6831-5p ; hsa-mir-4517 ; hsa-let-7g-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7f-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7i-5p ; hsa-let-7a-5p ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-mir-98-5p ; hsa-mir-335-3p ; hsa-mir-1305 ; hsa-mir-4276 ; hsa-mir-3140-3p ; hsa-mir-6770-5p ; hsa-mir-1253 ; hsa-mir-4502 ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-148a-3p ; hsa-mir-302c-3p ; hsa-mir-520f-3p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-29b-2-5p
Nearest miRNA
hsa-mir-8078/Upstream/300925; hsa-mir-1-2/Downstream/3472089;
Nearest TSS
ENST00000575820/Upstream/95898; ENST00000327228/Downstream/87458;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/144882, chr18-CpG: 182/Downstream/86051
Upstream sequence
atctcatttgaatatgggcagaagacatgaagagacatttgactgaagaagacagatggatggcaaataaacacatagaaagatattcaacatcactagc
Downstream sequence
cattagggtaatgtaaatcaaaggcataatgacataccactagacatctatcagaatggctgacataaaaaacggtgaccccacaaatgctggagaggat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate