Basic Information
VIS ID
TVIS44027572
Fusion event
HTLV-1-SETBP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
42335694/44755729 (Hg38)
End
42335694/44755729 (Hg38)
Orient
-
Location type
Intronic
Target gene
SETBP1
miRNAs that regulate target gene
hsa-mir-432-5p ; hsa-mir-218-5p ; hsa-mir-6819-5p ; hsa-mir-6812-5p ; hsa-mir-6737-5p ; hsa-mir-4766-3p ; hsa-mir-6742-5p ; hsa-mir-6769b-5p ; hsa-mir-6769a-5p ; hsa-mir-92a-2-5p ; hsa-mir-654-5p ; hsa-mir-541-3p ; hsa-mir-6747-5p ; hsa-mir-608 ; hsa-mir-4664-5p ; hsa-mir-4651 ; hsa-mir-6875-5p ; hsa-mir-342-5p ; hsa-mir-3126-5p ; hsa-mir-3908 ; hsa-mir-4735-5p ; hsa-mir-3942-5p ; hsa-mir-4703-5p ; hsa-mir-6873-5p ; hsa-mir-32-3p ; hsa-mir-4714-3p ; hsa-mir-520f-5p ; hsa-mir-4521 ; hsa-mir-3065-5p ; hsa-mir-4668-3p ; hsa-mir-651-3p ; hsa-mir-6873-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-7151-5p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4264 ; hsa-mir-4797-3p ; hsa-mir-4302 ; hsa-mir-6733-3p ; hsa-mir-5571-5p ; hsa-mir-4282
Nearest miRNA
hsa-mir-1-2/Upstream/5078950; hsa-mir-122/Downstream/214353;
Nearest TSS
ENST00000575820/Upstream/54391; ENST00000323329/Downstream/425385;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/10728, chr18-CpG: 19/Downstream/308011
Nearest cancer related gene
SETBP1(OG, No orient, 0)
Upstream sequence
ttttggacttggactgagcctctttgggagccacactactagttccctgggagacatgcttgtggctcctctggttttccagcttgcagacgatctctct
Downstream sequence
tgggactttgtgtttgtaatcatgtgagccaattcccccttaataagttccattttatatatatcccatttgtcctgtctctctggaagatcctaaccaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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