Basic Information
VIS ID
TVIS44027576
Fusion event
HTLV-1-CTIF integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
46310315/48783944 (Hg38)
End
46310315/48783944 (Hg38)
Orient
-
Location type
Intronic
Target gene
CTIF
miRNAs that regulate target gene
hsa-mir-877-3p ; hsa-mir-3147 ; hsa-mir-4689 ; hsa-mir-6858-5p ; hsa-mir-580-3p ; hsa-mir-449b-5p ; hsa-mir-449a ; hsa-mir-34c-5p ; hsa-mir-34a-5p ; hsa-mir-765 ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-539-5p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-708-5p ; hsa-mir-3139 ; hsa-mir-28-5p ; hsa-mir-1976 ; hsa-mir-6894-3p ; hsa-mir-4290 ; hsa-mir-18a-3p ; hsa-mir-5193 ; hsa-mir-4667-3p
Nearest miRNA
hsa-mir-1-2/Upstream/113276; hsa-mir-122/Downstream/265743;
Nearest TSS
ENST00000575820/Upstream/23762; ENST00000592658/Downstream/50826;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/22175, chr18-CpG: 20/Downstream/75951
Upstream sequence
GTCCACCGAGCCCCAGAGGCACCCAGTCAGCACTCACTCCCTCCAGCCTTACGTAGCGTCCACACGTATGCTGTTACCCACACGGGCCACCAAACCTCCA
Downstream sequence
GTCCCCTGCCCTATCTCACACACATCTTTACATTGCTCCATGTGCACTCTAGTGGGGATGGCCTTTTCCACACCAAGattcattcatttatcagctgagc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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