Basic Information
VIS ID
TVIS44027578
Fusion event
HTLV-1-DYM integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
46674141/49147771 (Hg38)
End
46674141/49147771 (Hg38)
Orient
+
Location type
Intronic
Target gene
DYM
miRNAs that regulate target gene
hsa-mir-941 ; hsa-mir-129-5p ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-106a-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-223-5p ; hsa-mir-6832-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p
Nearest miRNA
hsa-mir-1-2/Upstream/98003; hsa-mir-122/Downstream/339602;
Nearest TSS
ENST00000575820/Upstream/31470; ENST00000577641/Downstream/58141;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/171165, chr18-CpG: 74/Downstream/312363
Upstream sequence
tcattaaaaagtcaggaaacaacaggtgctggagaggatgtggagaaataggaacacttttacactgttggtgggactgtaaactagttcaaccattgtg
Downstream sequence
gaagtcagtgtggcgattcctcagggatctagaactacaaataccatttgacccggccatcccattactgggtatatacccaaaggagtataaaacatgc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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