Basic Information
VIS ID
TVIS44027580
Fusion event
HTLV-1-MYO5B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
47614538/50088168 (Hg38)
End
47614538/50088168 (Hg38)
Orient
-
Location type
Intronic
Target gene
MYO5B
miRNAs that regulate target gene
hsa-mir-103a-3p ; hsa-mir-16-5p ; hsa-mir-218-5p ; hsa-mir-587 ; hsa-mir-1229-3p ; hsa-mir-1304-3p
Nearest miRNA
hsa-mir-1-2/Upstream/600746; hsa-mir-122/Downstream/38331;
Nearest TSS
ENST00000575820/Upstream/185335; ENST00000586227/Downstream/9452;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/273582, chr18-CpG: 196/Downstream/105328
Upstream sequence
GAATTCATAGACCAGGGAAAGAAGCCAGCACCTGTGACACACAGCGGCAGGACCGGTGTGGGGTGACCTGCTGTTGGCTGTGGGTTTGGTGTCCAAAGGA
Downstream sequence
GGGTAGAAGGAAATAAACGTGGCAAGTCAGGATTATAGGTGGACCATGGAGGACCCCAAACACCCTGCTTGCAGAGAGGACTTCATGCTGTAAGCTACTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate