Basic Information
VIS ID
TVIS44027611
Fusion event
HTLV-1-ADNP2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q23
Reference genome
GRCh37/hg19
Start
77884851/80126968 (Hg38)
End
77884851/80126968 (Hg38)
Orient
+
Location type
Intronic
Target gene
ADNP2
miRNAs that regulate target gene
hsa-mir-224-5p ; hsa-mir-96-5p ; hsa-mir-141-3p ; hsa-mir-200a-3p ; hsa-mir-1224-5p ; hsa-mir-5004-5p ; hsa-mir-1305 ; hsa-mir-197-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-655-5p ; hsa-mir-4751
Nearest miRNA
hsa-mir-1-2/Upstream/7273586;
Nearest TSS
ENST00000575820/Upstream/9352; ENST00000588226/Downstream/20956;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/17212, chr18-CpG: 28/Downstream/20446
Upstream sequence
aaccacggtttgaaaatattatatggaaaattccagaaataaacaattcatctgttttaagttccatggcattctgagtTGTcttcatcttgtcacgtga
Downstream sequence
ggcgccacacaggcatcgtgtcatcgcatgccaccacaagaagggtgagcacaggatgtaagatactttgagagaccacattcacaaaacttttattact
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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