Basic Information
VIS ID
TVIS44027614
Fusion event
HTLV-1-RAB3D integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
11449118/11338442 (Hg38)
End
11449118/11338442 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
RAB3D
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-375 ; hsa-mir-508-5p ; hsa-mir-6736-5p ; hsa-mir-4701-3p ; hsa-mir-1262 ; hsa-mir-7703 ; hsa-mir-500a-3p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-542-3p ; hsa-mir-4792 ; hsa-mir-661 ; hsa-mir-767-5p ; hsa-mir-610 ; hsa-mir-6776-5p ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-6849-3p ; hsa-mir-6742-3p ; hsa-mir-1273g-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p
Nearest miRNA
hsa-mir-1181/Upstream/224908; hsa-let-7e/Downstream/157102;
Nearest TSS
ENST00000633603/Upstream/31718; ENST00000589186/Downstream/1226;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/44342, chr19-CpG: 38/Downstream/898
Upstream sequence
TCGCCCCAGCGTGTGCAGCCGGTGTGGCCCAGGTGTAAGCTGGGGTGGGGTGGGGGGAGGACCTGCCAGCTGGATAAGCTGGATAGAGCCCCTGATTAAG
Downstream sequence
GCTTGGGTGTTGACTTTGGCAGGTGTCAGCCACTGGGGCGCCTGCCGCCCACCAACTCATGCCAAATACAACCCCTTCTCTGAGTTCCAAGGGGAAGGGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate