Basic Information
VIS ID
TVIS44027620
Fusion event
HTLV-1-MEX3D integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
1559971/1559972 (Hg38)
End
1559971/1559972 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
MEX3D
miRNAs that regulate target gene
hsa-mir-744-5p ; hsa-mir-1913 ; hsa-mir-193a-3p ; hsa-mir-193b-3p ; hsa-mir-3148 ; hsa-mir-324-3p ; hsa-mir-337-5p ; hsa-mir-339-3p ; hsa-mir-4632-3p ; hsa-mir-4663 ; hsa-mir-651-3p ; hsa-mir-6752-3p ; hsa-mir-6757-3p ; hsa-mir-6801-3p ; hsa-mir-6810-3p
Nearest miRNA
hsa-mir-1302-11/Upstream/746319; hsa-let-7e/Downstream/256187;
Nearest TSS
ENST00000633603/Upstream/31635; ENST00000586506/Downstream/7558;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/3105, chr19-CpG: 241/Downstream/6706
Upstream sequence
gccccagctgcactgccaccacacctgtccctcccagtcgcagcattctgttcacctccattgcacccagtcccctccattcttctgtacagtccggtgt
Downstream sequence
ccccctcctccaggaagcccaccctgactgcatcgggttgggcctgctcttctgagtctctcctaacatgcctgactctctgagctGCCTCCCTGAGGCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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