Basic Information
VIS ID
TVIS44027623
Fusion event
HTLV-1-ISYNA1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.11
Reference genome
GRCh37/hg19
Start
18549450/18438640 (Hg38)
End
18549450/18438640 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
ISYNA1
miRNAs that regulate target gene
hsa-mir-197-3p ; hsa-mir-320a
Nearest miRNA
hsa-mir-10395/Upstream/52006; hsa-let-7e/Downstream/996423;
Nearest TSS
ENST00000633603/Upstream/339; ENST00000594590/Downstream/2779;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/289, chr19-CpG: 24/Downstream/7588
Nearby gene
ISYNA1(-339) ;
Upstream sequence
TCTCCTCGGAGCCACACTGCCACCTACTCCCCCTTCGTGGGCAGCAGCACCTACCAGGCAGTCCCATCCCCTGGCTCCCCATGTCCGCCCCCATCCATCT
Downstream sequence
CGGGGGACAAAGTCACTCTGTCCCCACGGGGCTCACAAGGATGGGGCCTGTTTGGCCTGTTTCCCCACCTGCAGCAGGAGGGCTTGGCAGGAGTGGGCCG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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