Basic Information
VIS ID
TVIS44027649
Fusion event
HTLV-1-PIP5K1C integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
3683425/3683427 (Hg38)
End
3683425/3683427 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
PIP5K1C
miRNAs that regulate target gene
hsa-mir-101-3p ; hsa-mir-32-5p ; hsa-mir-26b-5p ; hsa-mir-193b-3p ; hsa-mir-4325 ; hsa-mir-7703 ; hsa-mir-6807-5p ; hsa-mir-6727-5p ; hsa-mir-5705 ; hsa-mir-6751-3p ; hsa-mir-1199-5p ; hsa-mir-4787-5p ; hsa-mir-6871-5p ; hsa-mir-496 ; hsa-mir-92b-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-25-3p ; hsa-mir-92a-3p ; hsa-mir-6875-3p ; hsa-mir-670-3p ; hsa-mir-6815-3p ; hsa-mir-103a-2-5p ; hsa-mir-4778-3p ; hsa-mir-3664-3p ; hsa-mir-5000-3p ; hsa-mir-4436a ; hsa-mir-1197
Nearest miRNA
hsa-mir-1227/Upstream/1052634; hsa-let-7e/Downstream/277987;
Nearest TSS
ENST00000633603/Upstream/10845; ENST00000587912/Downstream/16963;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/6842, chr19-CpG: 38/Downstream/4361
Upstream sequence
TGGGCTTGGCTCAGGAGGGAAACGGGGTTGGATGGGGTCAAGAGCCCAGGGGCGCAGGCTGCTTCCCGTCTCTAACCACTGAGCCACCCTGGAACAGCTG
Downstream sequence
GAGCGCAGGCAGGAGCTGGCCAGAGACGAGCTAGCCCACCTTCGCCGTGTGTGTGGCGGGGCCCGCACCATATGAGAACCCcatggcttagtcacgcaat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate