Basic Information
VIS ID
TVIS44027653
Fusion event
HTLV-1-PSMD8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
38873316/38382676 (Hg38)
End
38873316/38382676 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
PSMD8
miRNAs that regulate target gene
hsa-mir-425-5p ; hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-423-3p ; hsa-mir-186-5p ; hsa-mir-149-5p ; hsa-mir-196a-5p
Nearest miRNA
hsa-mir-10395/Upstream/3037049; hsa-let-7e/Downstream/1026947;
Nearest TSS
ENST00000633603/Upstream/1777; ENST00000585411/Downstream/2846;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/7583, chr19-CpG: 208/Downstream/2754
Upstream sequence
GGCTGGGACCAGGCTATGGAAGGTGAAATTGGGCTGGGTGCAGTGGCTCCCGCGCACCAAGGTGGATCCTCCCACCTAGGCTcactctgggaggctgagg
Downstream sequence
tgggaggatcgcctgaggtcaggagttcgagaccagcctggtcaacatggtgaaacctcatctctactaaaaaatacaaaaaaaattagccggatgtggt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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