Basic Information
VIS ID
TVIS44027661
Fusion event
HTLV-1-GRIK5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
42546763/42042611 (Hg38)
End
42546763/42042611 (Hg38)
Orient
+
Location type
Exonic
Fragile sites / regions
FRA19A
Target gene
GRIK5
miRNAs that regulate target gene
hsa-mir-186-5p ; hsa-mir-4795-3p ; hsa-mir-126-5p
Nearest miRNA
hsa-mir-10395/Upstream/172913; hsa-let-7e/Downstream/90834;
Nearest TSS
ENST00000633603/Upstream/38847; ENST00000597391/Downstream/290;
Nearest CpG islands
chr19-CpG: 25/Target, None/Upstream, None/Downstream
Upstream sequence
CCGGGTCCATGCATCTTTCCCGGCCCCAGTCCAGCCATACCCGGTTGATGAGCTCGCCAACCATGCCCGTCCAGGAGCCGTTGGGCTCGGGCGCCCCGTA
Downstream sequence
CAGCCCATCCTCCACCAACCGCAGGCGGTAGCGGAAGCGCAGCAGCTCGGCCAGCTCCCGCAGCATGTCCACGCAGAAGCCCTCGAAGCGTTCGTTCCCC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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