Basic Information
VIS ID
TVIS44027674
Fusion event
HTLV-1-PRR12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
50100743/49597486 (Hg38)
End
50100743/49597486 (Hg38)
Orient
+
Location type
Exonic
Fragile sites / regions
FRA19A
Target gene
PRR12
miRNAs that regulate target gene
hsa-mir-744-5p ; hsa-mir-615-3p ; hsa-mir-320a ; hsa-mir-34a-5p ; hsa-mir-92a-3p ; hsa-mir-16-5p ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-6515-5p ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-6848-5p ; hsa-mir-7847-3p ; hsa-mir-6846-5p ; hsa-mir-6825-5p ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-3175 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-6797-5p ; hsa-mir-149-3p ; hsa-mir-1249-5p ; hsa-mir-766-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4419a ; hsa-mir-4510 ; hsa-mir-194-3p ; hsa-mir-6805-5p ; hsa-mir-4786-5p ; hsa-mir-6849-3p ; hsa-mir-1273g-3p ; hsa-mir-4666b ; hsa-mir-5011-3p ; hsa-mir-6076 ; hsa-mir-6797-3p ; hsa-mir-6807-5p
Nearest miRNA
hsa-mir-10395/Upstream/96618; hsa-let-7e/Downstream/84631;
Nearest TSS
ENST00000633603/Upstream/1964; ENST00000593853/Downstream/22963;
Nearest CpG islands
chr19-CpG: 86/Target, None/Upstream, None/Downstream
Upstream sequence
CTGCCCTCCACGGTCAACGCCGAGCCGCTGGGCCTGATCCAGAGTGGCCCCCACCAGGCGGcgccaccacccccgcctccgccaccgccgcctcccgcgc
Downstream sequence
cGGCCTCCGAACCCAAGGGTGGCCTCACCTCGCCCATCTTCTGCTCTACCAAGCCAAAGAAGCTGCTCAAGACATCCTCCTTCCACCTGCTGCGGCGCCG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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