Basic Information
VIS ID
TVIS44027677
Fusion event
HTLV-1-KDM4B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
5082585/5082574 (Hg38)
End
5082585/5082574 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
KDM4B
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-505-5p ; hsa-mir-106b-3p ; hsa-mir-615-3p ; hsa-mir-491-5p
Nearest miRNA
hsa-mir-1227/Upstream/149834; hsa-let-7e/Downstream/1307064;
Nearest TSS
ENST00000633603/Upstream/122; ENST00000592159/Downstream/29784;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/5680, chr19-CpG: 17/Downstream/10853
Upstream sequence
TGGATTGACTACGGCAAAGTGGCCACTCAGGTAAAAGCTTGCCTGCTGGGAACGGGTCCCAGCAGGGCGGGAGGAGGCTCTTTTTTGCCTCTGCAGCCAC
Downstream sequence
ACGCCCATAGCTGGTCCAGCAGCCGTTTCGCTCAGCCCAGGGCCTGGGCTCTCAACCAGGGTCTGATTCTGGGCTCCTCAGAGAGCTTTTGCCCAGAACG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate