Basic Information
VIS ID
TVIS44027688
Fusion event
HTLV-1-GPR108 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
6733875/6733864 (Hg38)
End
6733875/6733864 (Hg38)
Orient
+
Location type
Exonic
Fragile sites / regions
FRA19B
Target gene
GPR108
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-185-5p
Nearest miRNA
hsa-mir-1227/Upstream/317353; hsa-let-7e/Downstream/2848;
Nearest TSS
ENST00000633603/Upstream/563; ENST00000596543/Downstream/2920;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/26308, chr19-CpG: 59/Downstream/3364
Upstream sequence
GGTAGGGCTGCAGGAGGGCTCAGCTTGGGGGTCCCGTGCTCTGGGGTGACGGAAGGGCCGCAGGCGCTGCAAACACTCACACTGAAGTTGTAGGAGTTGT
Downstream sequence
TGAGGTGGCTCAGGCCCAACACCAGGTCCTTGTCCTTCCCACTAGGACCCTGAAGGGACAGAGCCCCTCCATCAGCTGGTTCTGGGTCCCCGCAGGGCCC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate