Basic Information
VIS ID
TVIS44027690
Fusion event
HTLV-1-INSR integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
7172031/7172020 (Hg38)
End
7172031/7172020 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
INSR
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-195-5p ; hsa-mir-7108-3p ; hsa-mir-15b-5p
Nearest miRNA
hsa-mir-1227/Upstream/435242; hsa-let-7e/Downstream/445419;
Nearest TSS
ENST00000633603/Upstream/4042; ENST00000576789/Downstream/121846;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/28922, chr19-CpG: 27/Downstream/25084
Upstream sequence
ttttttttttggacagagtctcactctgtcacccaggctggagtgcagtagtgtgatcttggctcactgcaacctctgcctcccaggttcaagctattct
Downstream sequence
cctgcctcagcctcccaagtagctgggattacaggcatgcactatcacacttggctaatttttgtacttttagtagagacagggtttcaccatgttggcc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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