Basic Information
VIS ID
TVIS44027696
Fusion event
HTLV-1-FBN3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
8201657/8136773 (Hg38)
End
8201657/8136773 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
FBN3
miRNAs that regulate target gene
hsa-mir-132-3p ; hsa-mir-221-3p
Nearest miRNA
hsa-mir-1227/Upstream/519268; hsa-let-7e/Downstream/252517;
Nearest TSS
ENST00000633603/Upstream/24967; ENST00000600912/Downstream/10993;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/307, chr19-CpG: 89/Downstream/12286
Upstream sequence
AGAGTCCTGCCTTAGATTCAGAACTCCAACCTGGGATCTAGATCCCTCCAACCTGGGACCTAGATCCCTCCAACCTGGGCCTGGATCCCTCCAACCTGGG
Downstream sequence
GCCTGGATCCCTCCAACCTGGGCCTGGATCCCTCCAACCTGGGGTCTAGATACCTCCAACCTGGGGCCTGGATCCCTCCAACCTGGGACCTGGATCCCTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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