Basic Information
VIS ID
TVIS44027709
Fusion event
HTLV-1-KIF16B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
16405339/16424694 (Hg38)
End
16405339/16424694 (Hg38)
Orient
-
Location type
Intronic
Target gene
KIF16B
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-7-5p ; hsa-mir-221-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/5774999; hsa-mir-1-1/Downstream/2045921;
Nearest TSS
ENST00000382410/Upstream/19827; ENST00000616572/Downstream/148739;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/2428272, chr20-CpG: 50/Downstream/148497
Upstream sequence
TCTTTCTTTCCCTCATTCTTACATAGTTCAGCCCAAAAACTATTACGCAGGCAAAAGCAAAGTAGGCATCAGCATGAGAGTGGAGGCAAATGGCATGGGC
Downstream sequence
TGAGAAAAGTTTCTGCACTGTGGAAGGGTGAGGGCCATGACAGCCAAGCATAGCCATGCTTGTGGTCTGAGCAAGAAGAGGAGGGTCCCAGTGTGAGGAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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