Basic Information
VIS ID
TVIS44027711
Fusion event
HTLV-1-ZNF133 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
p11.23
Reference genome
GRCh37/hg19
Start
18290309/18309665 (Hg38)
End
18290309/18309665 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA20A
Target gene
ZNF133
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/7659970; hsa-mir-1-1/Downstream/160950;
Nearest TSS
ENST00000382410/Upstream/4580; ENST00000462170/Downstream/2971;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/20904, chr20-CpG: 65/Downstream/157120
Upstream sequence
GCATTCACAGTGCAGGTGAGGTCAGTGTTGCTGAGAAGTTGGAGTCTTAGCCAGAGGCTCAGCCCTGTGGAGCACCCTGAGAGTGCTGACAGGTATTGGT
Downstream sequence
GTGGAGAGGATGTGAGGCTGGTAGGTGATCAAATATTCAGGGCAGTGTGTGAAACCAGGAGACCTGTGGATGGTCCTAAAAAAAGTATGGTAGGTaatgg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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