Basic Information
VIS ID
TVIS44027712
Fusion event
HTLV-1-SIRPA integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
p13
Reference genome
GRCh37/hg19
Start
1910883/1930237 (Hg38)
End
1910883/1930237 (Hg38)
Orient
-
Location type
Intronic
Target gene
SIRPA
miRNAs that regulate target gene
hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-106a-5p ; hsa-mir-615-3p ; hsa-mir-4509 ; hsa-mir-4744 ; hsa-mir-6731-3p ; hsa-mir-1245a ; hsa-mir-1287-3p ; hsa-mir-2355-5p ; hsa-mir-1251-5p ; hsa-mir-4286 ; hsa-mir-6777-3p ; hsa-mir-141-5p ; hsa-mir-6783-5p ; hsa-mir-6769a-3p ; hsa-mir-3943 ; hsa-mir-4323 ; hsa-mir-5684 ; hsa-mir-1262 ; hsa-mir-1293 ; hsa-mir-140-5p ; hsa-mir-203b-5p ; hsa-mir-3165 ; hsa-mir-323a-5p ; hsa-mir-363-5p ; hsa-mir-3689d ; hsa-mir-4259 ; hsa-mir-4460 ; hsa-mir-4483 ; hsa-mir-4536-5p ; hsa-mir-4701-3p ; hsa-mir-6718-5p ; hsa-mir-6736-5p ; hsa-mir-6741-5p ; hsa-mir-6745 ; hsa-mir-6756-5p ; hsa-mir-6766-5p ; hsa-mir-6851-5p ; hsa-mir-6880-5p ; hsa-mir-7847-3p ; hsa-mir-8071 ; hsa-mir-876-3p
Nearest miRNA
hsa-mir-6869/Upstream/537276; hsa-mir-1-1/Downstream/722540;
Nearest TSS
ENST00000382410/Upstream/34941; ENST00000446562/Downstream/17009;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/34686, chr20-CpG: 15/Downstream/7194
Upstream sequence
ttatgcaatgTGGTAGCTAGAGTGGGACCCCTCCTGTCACCTGCTCACCTCCTGCTTCTCCTGAGATCAGCAAGGGCACGACatcctccagggtcggagg
Downstream sequence
gcttcctgtgaaccctcctggtgccgcagcgtggacaccctggtgtgttcaaggtgtctctgcacctgtcccatttcataacccacccctcaaggccagg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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