Basic Information
VIS ID
TVIS44027743
Fusion event
HTLV-1-PHF20 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
34369730/35781808 (Hg38)
End
34369730/35781808 (Hg38)
Orient
-
Location type
Intronic
Target gene
PHF20
miRNAs that regulate target gene
hsa-mir-197-3p ; hsa-mir-21-5p ; hsa-mir-1303 ; hsa-mir-5096 ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-6802-3p ; hsa-mir-411-5p ; hsa-mir-6832-5p ; hsa-mir-193b-5p ; hsa-mir-3620-3p ; hsa-mir-6865-3p ; hsa-mir-483-5p ; hsa-mir-10b-5p ; hsa-mir-10a-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/327711; hsa-mir-1-1/Downstream/2734755;
Nearest TSS
ENST00000382410/Upstream/9775; ENST00000496305/Downstream/67581;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/9480, chr20-CpG: 146/Downstream/171872
Upstream sequence
ctgaggcaggtagatcacttgaggtcaggagttcgaggccagcctggccatcatggcaaaaccccatctctactaaaaatacaaaaattagctgggcgtg
Downstream sequence
gtagcacatgcctgtgatcccagccactagggagcctgaagcaggagaactgtttgaacgcgggggcgggtggaggttgcactgagccaggattgctgca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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