Basic Information
VIS ID
TVIS44027748
Fusion event
HTLV-1-CTNNBL1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
36473988/37845586 (Hg38)
End
36473988/37845586 (Hg38)
Orient
-
Location type
Intronic
Target gene
CTNNBL1
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-1229-3p ; hsa-mir-320a ; hsa-mir-149-5p ; hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-mir-129-5p ; hsa-mir-4482-3p ; hsa-mir-7159-3p ; hsa-mir-4715-3p ; hsa-mir-4775 ; hsa-mir-661 ; hsa-mir-3116 ; hsa-mir-1254 ; hsa-mir-664a-5p ; hsa-mir-4794 ; hsa-mir-138-2-3p ; hsa-mir-4735-5p ; hsa-mir-6872-3p ; hsa-mir-590-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/2391489; hsa-mir-1-1/Downstream/670977;
Nearest TSS
ENST00000382410/Upstream/3332; ENST00000481674/Downstream/2272;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/151402, chr20-CpG: 101/Downstream/57155
Upstream sequence
CTGGCAAACATTCCAAGGCCATTAGTGCTCAGCAGCCTCAGTGTTACGCAGAGAGCCAGGGCAGGTAGGGGTGAGGGATGCGTTTGTGAGCAGTGTTTGC
Downstream sequence
TGCTAGCACTCAGGCGCCATCCTAGCAGATGAAGCCGCCTCACAGGTGTAAAGTGACTTAGAACAATACGACCTCCTTTTCACCTCTGCCTCATGCCGTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate