Basic Information
VIS ID
TVIS44027755
Fusion event
HTLV-1-ARHGAP40 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
37258932/38630289 (Hg38)
End
37258932/38630289 (Hg38)
Orient
+
Location type
Intronic
Target gene
ARHGAP40
miRNAs that regulate target gene
hsa-mir-4474-3p ; hsa-mir-185-3p ; hsa-mir-762 ; hsa-mir-5001-5p ; hsa-mir-4498 ; hsa-mir-4492 ; hsa-mir-6131 ; hsa-mir-187-5p ; hsa-mir-4508 ; hsa-mir-6784-5p ; hsa-mir-4532
Nearest miRNA
hsa-mir-103a-2/Upstream/113657; hsa-mir-1-1/Downstream/2538734;
Nearest TSS
ENST00000382410/Upstream/3293; ENST00000373346/Downstream/13618;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/28190, chr20-CpG: 39/Downstream/15759
Upstream sequence
ccttttcttcttcctttctttccttctttccttcttttttttttctttgagacaaggtctcactctgtcacccaggcgggagtgcagtggtaccatccca
Downstream sequence
gctcactgcagcctcaacctcccaggctcaagctatccttacacctcagtctctcaagtagctaggactacagttgcatgccaccatgcccagctaattt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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