Basic Information
VIS ID
TVIS44027756
Fusion event
HTLV-1-DHX35 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q12
Reference genome
GRCh37/hg19
Start
37662409/39033766 (Hg38)
End
37662409/39033766 (Hg38)
Orient
+
Location type
Intronic
Target gene
DHX35
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-16-5p ; hsa-mir-545-3p ; hsa-mir-330-3p ; hsa-mir-3120-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/517134; hsa-mir-1-1/Downstream/2135257;
Nearest TSS
ENST00000382410/Upstream/3406; ENST00000444436/Downstream/190982;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/71225, chr20-CpG: 59/Downstream/16164
Upstream sequence
TTCGGTTGTCTATTACCTGAGCCTTAGAAACATTTTTTCCCTTAAATAAAGGTATAATTTATTtacagtgcaagatgagttttgacaaatgtgtataccc
Downstream sequence
atgtaacctggacccacataaattatacaatattgttatcattttagaaaattcctttgtgtctctttacagtcagttcccagcctcTTTCAGAATCAGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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