Basic Information
VIS ID
TVIS44027763
Fusion event
HTLV-1-TOX2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
42554006/43925366 (Hg38)
End
42554006/43925366 (Hg38)
Orient
+
Location type
Intronic
Target gene
TOX2
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/2756288; hsa-mir-1-1/Downstream/482754;
Nearest TSS
ENST00000382410/Upstream/9199; ENST00000435864/Downstream/20339;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/8869, chr20-CpG: 79/Downstream/190316
Upstream sequence
GATCTGTTCTGTGGTTGTGAGTTTCCTCAACATGGGTGAAAGCCGTGACTGCGTGGGTGGGCAGGGTGGATGTTGAGTAGAAACGCTCTGTGTGTGGTGT
Downstream sequence
GTGAGTGCAGACTCTATTGCGGTGTGGGATGAGCCTACGAAGTCCTTGGGGGCCTCTTTGTCCCTCGGGTAGGCCAGCAGTTACCCCCAGGGCGCTGGTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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