Basic Information
VIS ID
TVIS44027768
Fusion event
HTLV-1-EYA2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
45656412/47027773 (Hg38)
End
45656412/47027773 (Hg38)
Orient
-
Location type
Intronic
Target gene
EYA2
miRNAs that regulate target gene
hsa-mir-30a-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/1322593; hsa-mir-1-1/Downstream/139194;
Nearest TSS
ENST00000382410/Upstream/26313; ENST00000475856/Downstream/61466;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/132392, chr20-CpG: 38/Downstream/211137
Upstream sequence
GGAGGGAGTTTAGTTCAACAGCAATTTGCTAAGGcagtgctgtccaacagacccttctgtgatgatggaaatcctctgagtggctgtgcaacgtgatagc
Downstream sequence
ccctagccacaggtggctactgagcactgaaatgtggttagtgcaactgaggaattgaatttttaattttgtttaattttaattaattgtaaatGCACCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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