Basic Information
VIS ID
TVIS44027775
Fusion event
HTLV-1-ARFGEF2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.13
Reference genome
GRCh37/hg19
Start
47585558/48969021 (Hg38)
End
47585558/48969021 (Hg38)
Orient
+
Location type
Intronic
Target gene
ARFGEF2
miRNAs that regulate target gene
hsa-mir-766-3p ; hsa-mir-484 ; hsa-mir-20a-5p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-335-3p ; hsa-mir-539-5p ; hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-5696 ; hsa-mir-329-5p ; hsa-mir-552-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/1801963; hsa-mir-1-1/Downstream/894838;
Nearest TSS
ENST00000382410/Upstream/47131; ENST00000493140/Downstream/29079;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/46960, chr20-CpG: 79/Downstream/77174
Upstream sequence
ATTTCTAATTTTTGATAAGAGTTAGCTTTTGTTTTGTCCTCTCCCtttttattttttgagatacggtctcactatgttccccagattggagtgcaatggt
Downstream sequence
gccatcatggcttactgcagccttgacctcctcggctcagtggatcctcctgcctcagcctctggagtagctgggactacaggtgggtgccaccacaccc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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